Systemic Lupus Erythematosus
What is Systemic Lupus Erythematosus?
SLE is also known as discoid lupus or disseminated lupus erythematosus. Although “lupus” actually includes a number of different diseases, SLE is the most common type of lupus, and when people say “lupus,” they are often referring to SLE.
SLE is a chronic disease that can have phases of worsening symptoms that alternate with periods of mild symptoms. Luckily, most people with SLE lead a normal life.
According to the Lupus Foundation of America, at least 1.5 million Americans are living with diagnosed lupus (LFA). The Foundation believes that the number of people who actually suffer from the condition is likely much higher—and that many cases go undiagnosed.
Causes of SLE
Genetics
The disease is not linked to a certain gene, but people with lupus often have family members with other autoimmune conditions.
Environment
There may be environmental triggers like ultraviolet rays, certain medications, a virus, physical or emotional stress, and trauma.
Gender and Hormones
SLE affects more women than men. Women also experience worsening of symptoms during pregnancy and with their menstrual periods. Both of these observations have led some medical professionals to believe that the female hormone estrogen may play a role in causing SLE. However, more research is still needed to prove this theory.
Recognizing Potential Symptoms of SLE
The typical "butterfly" rash |
• painful or swollen joints
• headaches
• rash on cheeks and nose called “butterfly” rash
• hair loss
• anemia
• blood-clotting problems
• Raynaud’s syndrome (fingers turning white/blue and tingle when cold)
Other symptoms can depend on the part of the body the disease is attacking, such as the digestive tract, the heart, or skin.
Lupus symptoms are also symptoms of many other diseases, which makes diagnosis tricky. If you have any of these symptoms, see your doctor. Your doctor can run tests to gather the information needed to make an accurate diagnosis.
How is SLE Diagnosed?
• blood tests, such as antibody tests and a complete blood count
• urinalysis
• chest X-ray
Cardiac Tamponade With Fibrin Strands Leading to the Diagnosis of Systemic Lupus Erythematosus |
Your general practitioner might refer you to a doctor called a rheumatologist. Rheumatologists specialize in treating joint and soft tissue disorders and autoimmune diseases.
Treatment for SLE
• anti-inflammatory medications for joint pain and stiffness
• steroid creams for rashes
• corticosteroids of varying doses to minimize the immune response
• antimalarial drugs for skin and joint problems
Talk with your doctor about your diet and lifestyle habits. Your doctor might recommend eating or avoiding certain foods and minimizing stress to reduce the likelihood of triggering symptoms. You might need to have screenings for osteoporosis, since steroids can thin your bones. Preventative care such as immunizations and cardiac screenings may also be recommended.
Potential Long-Term Complications of SLE
Lupus can take an emotional toll. Working with a trained counselor or support group in your area can help you reduce stress, maintain positive mental health, and manage your illness.
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